Ontology highlight
ABSTRACT:
SUBMITTER: Kidd LR
PROVIDER: S-EPMC3155982 | biostudies-literature | 2011 Feb
REPOSITORIES: biostudies-literature
Kidd LaCreis R LR Hein David W DW Woodson Karen K Taylor Philip R PR Albanes Demetrius D Virtamo Jarmo J Tangrea Joseph A JA
Biochemical genetics 20101008 1-2
Genetic variations in xenobiotic metabolizing genes can influence susceptibility to many environmentally induced cancers. Inheritance of the N-acetyltransferase 1 allele (NAT1*10), linked with increased metabolic activation of pro-carcinogens, is associated with an increased susceptibility to many cancers in which cigarette- or meat-derived carcinogens have been implicated in their etiology. The role of NAT1*10 in prostate cancer is under studied. Although cigarette smoking is not considered a r ...[more]