Ontology highlight
ABSTRACT:
SUBMITTER: Du Pasquier D
PROVIDER: S-EPMC3156807 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
PloS one 20110816 8
Ovulated eggs possess maternal apoptotic execution machinery that is inhibited for a limited time. The fertilized eggs switch off this time bomb whereas aged unfertilized eggs and parthenogenetically activated eggs fail to stop the timer and die. To investigate the nature of the molecular clock that triggers the egg decision of committing suicide, we introduce here Xenopus eggs as an in vivo system for studying the death of unfertilized eggs. We report that after ovulation, a number of eggs rema ...[more]