Determination of the Plasmodium vivax schizont stage proteome.
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ABSTRACT:
SUBMITTER: Roobsoong W
PROVIDER: S-EPMC3156846 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Publications
Determination of the Plasmodium vivax schizont stage proteome.
Roobsoong Wanlapa W Roytrakul Sittiruk S Sattabongkot Jetsumon J Li Jianyong J Udomsangpetch Rachanee R Cui Liwang L
Journal of proteomics 20110413 9
With the genome of the malaria parasite Plasmodium vivax sequenced, it is important to determine the proteomes of the parasite in order to assist efforts in antigen and drug target discovery. Since a method for continuous culture of P. vivax parasite is not available, we tried to study the proteome of the erythrocytic stages using fresh parasite isolates from patients. In schizont-enriched samples, 316 proteins were confidently identified by tandem mass spectrometry. Almost 50% of the identified ...[more]
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