Ontology highlight
ABSTRACT:
SUBMITTER: Kim KH
PROVIDER: S-EPMC3158501 | biostudies-literature | 2011 Jul
REPOSITORIES: biostudies-literature
Kim Kang Ho KH Yoo Hae Yong HY Joo Kyeung Min KM Jung Yong Y Jin Juyoun J Kim Yonghyun Y Yoon Su Jin SJ Choi Seung Ho SH Seol Ho Jun HJ Park Woong Yang WY Nam Do Hyun DH
Experimental & molecular medicine 20110701 7
Radiation is the most useful treatment modality for cancer patients. It initiates a series of signal cascades such as DNA damage response (DDR) signaling for repairing damaged DNA, arresting the cell cycle, and inducing cell death. Until now, few genes have been found to be regulated by radiation, which explains the molecular mechanisms of cellular responses to radiation. Although the transcriptional changes caused by radiation have been widely investigated, little is known about the direct evid ...[more]