Ontology highlight
ABSTRACT:
SUBMITTER: Elpek KG
PROVIDER: S-EPMC3158776 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Elpek Kutlu G KG Bellemare-Pelletier Angelique A Malhotra Deepali D Reynoso Erika D ED Lukacs-Kornek Veronika V DeKruyff Rosemarie H RH Turley Shannon J SJ
PloS one 20110819 8
Lymphoid organ-resident DC subsets are thought to play unique roles in determining the fate of T cell responses. Recent studies focusing on a single lymphoid organ identified molecular pathways that are differentially operative in each DC subset and led to the assumption that a given DC subset would more or less exhibit the same genomic and functional profiles throughout the body. Whether the local milieu in different anatomical sites can also influence the transcriptome of DC subsets has remain ...[more]