A vestige of a prebiotic bonding machine is functioning within the contemporary ribosome.
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ABSTRACT:
SUBMITTER: Krupkin M
PROVIDER: S-EPMC3158926 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
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A vestige of a prebiotic bonding machine is functioning within the contemporary ribosome.
Krupkin Miri M Matzov Donna D Tang Hua H Metz Markus M Kalaora Rinat R Belousoff Matthew J MJ Zimmerman Ella E Bashan Anat A Yonath Ada A
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20111001 1580
Based on the presumed capability of a prebiotic pocket-like entity to accommodate substrates whose stereochemistry enables the creation of chemical bonds, it is suggested that a universal symmetrical region identified within all contemporary ribosomes originated from an entity that we term the 'proto-ribosome'. This 'proto-ribosome' could have evolved from an earlier machine that was capable of performing essential tasks in the RNA world, called here the 'pre-proto-ribosome', which was adapted f ...[more]
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