Ontology highlight
ABSTRACT:
SUBMITTER: Araya CL
PROVIDER: S-EPMC3159719 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Araya Carlos L CL Fowler Douglas M DM
Trends in biotechnology 20110510 9
Analysis of protein mutants is an effective means to understand their function. Protein display is an approach that allows large numbers of mutants of a protein to be selected based on their activity, but only a handful with maximal activity have been traditionally identified for subsequent functional analysis. However, the recent application of high-throughput sequencing (HTS) to protein display and selection has enabled simultaneous assessment of the function of hundreds of thousands of mutant ...[more]