Ontology highlight
ABSTRACT:
SUBMITTER: Cheon CH
PROVIDER: S-EPMC3161142 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20110804 34
A chiral Brønsted acid has been developed from a cationic gold(I) disphosphine complex in the presence of alcoholic solvent and applied to the enantioselective protonation reaction of silyl enol ethers of ketones. Various optically active cyclic ketones were obtained in excellent yields and high enantioselectivities, including cyclic ketones bearing aliphatic substrates at the α-position. Furthermore, the application of this Brønsted acid was extended to the first Brønsted acid-catalyzed enantio ...[more]