Antipsychotic drugs and heart muscle disorder in international pharmacovigilance: data mining study.
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ABSTRACT:
SUBMITTER: Coulter DM
PROVIDER: S-EPMC31617 | biostudies-literature | 2001 May
REPOSITORIES: biostudies-literature
Publications
Antipsychotic drugs and heart muscle disorder in international pharmacovigilance: data mining study.
Coulter D M DM Bate A A Meyboom R H RH Lindquist M M Edwards I R IR
BMJ (Clinical research ed.) 20010501 7296
<h4>Objectives</h4>To examine the relation between antipsychotic drugs and myocarditis and cardiomyopathy.<h4>Design</h4>Data mining using bayesian statistics implemented in a neural network architecture.<h4>Setting</h4>International database on adverse drug reactions run by the World Health Organization programme for international drug monitoring.<h4>Main outcome measures</h4>Reports mentioning antipsychotic drugs, cardiomyopathy, or myocarditis.<h4>Results</h4>A strong signal existed for an as ...[more]
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