Dataset Information

Evolvable neuronal paths: a novel basis for information and search in the brain.

ABSTRACT: We propose a previously unrecognized kind of informational entity in the brain that is capable of acting as the basis for unlimited hereditary variation in neuronal networks. This unit is a path of activity through a network of neurons, analogous to a path taken through a hidden Markov model. To prove in principle the capabilities of this new kind of informational substrate, we show how a population of paths can be used as the hereditary material for a neuronally implemented genetic algorithm, (the swiss-army knife of black-box optimization techniques) which we have proposed elsewhere could operate at somatic timescales in the brain. We compare this to the same genetic algorithm that uses a standard 'genetic' informational substrate, i.e. non-overlapping discrete genotypes, on a range of optimization problems. A path evolution algorithm (PEA) is defined as any algorithm that implements natural selection of paths in a network substrate. A PEA is a previously unrecognized type of natural selection that is well suited for implementation by biological neuronal networks with structural plasticity. The important similarities and differences between a standard genetic algorithm and a PEA are considered. Whilst most experiments are conducted on an abstract network model, at the conclusion of the paper a slightly more realistic neuronal implementation of a PEA is outlined based on Izhikevich spiking neurons. Finally, experimental predictions are made for the identification of such informational paths in the brain.

SUBMITTER: Fernando C

PROVIDER: S-EPMC3162558 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature

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Evolvable neuronal paths: a novel basis for information and search in the brain.

Fernando Chrisantha C Vasas Vera V Szathmáry Eörs E Husbands Phil P

PloS one 20110826 8

We propose a previously unrecognized kind of informational entity in the brain that is capable of acting as the basis for unlimited hereditary variation in neuronal networks. This unit is a path of activity through a network of neurons, analogous to a path taken through a hidden Markov model. To prove in principle the capabilities of this new kind of informational substrate, we show how a population of paths can be used as the hereditary material for a neuronally implemented genetic algorithm, ( ...[more]

PMID: 21887266

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Dataset Information

Evolvable neuronal paths: a novel basis for information and search in the brain.

Publications

Evolvable neuronal paths: a novel basis for information and search in the brain.

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