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MicroRNAs in Parkinson's disease.

ABSTRACT: MicroRNAs are small non-protein coding RNAs that regulate gene expression through post-transcriptional repression. Recent studies demonstrated the importance of microRNAs in the nervous system development, function and disease. Parkinson's disease is the second most prevalent neurodegenerative disease with only symptomatic treatment available. Recent success in using small RNAs as therapeutic targets hold a substantial promise for the Parkinson's disease field. Here we review recent work linking the microRNA pathway to Parkinson's disease.

SUBMITTER: Harraz MM

PROVIDER: S-EPMC3163813 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature

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MicroRNAs in Parkinson's disease.

Harraz Maged M MM Dawson Ted M TM Dawson Valina L VL

Journal of chemical neuroanatomy 20110202 2

MicroRNAs are small non-protein coding RNAs that regulate gene expression through post-transcriptional repression. Recent studies demonstrated the importance of microRNAs in the nervous system development, function and disease. Parkinson's disease is the second most prevalent neurodegenerative disease with only symptomatic treatment available. Recent success in using small RNAs as therapeutic targets hold a substantial promise for the Parkinson's disease field. Here we review recent work linking ...[more]

PMID: 21295133

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