Homology modeling and consensus protein disorder prediction of human filamin.
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ABSTRACT:
SUBMITTER: Kumar S
PROVIDER: S-EPMC3163912 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
Homology modeling and consensus protein disorder prediction of human filamin.
Bioinformation 20110802 10
Filamins are dimeric actin-binding proteins participating in the organization of the actin-based cytoskeleton. Their modular domain organization is made up of an N-terminal actin-binding domain composed of two CH domains followed by flexible rod regions that consist of 24 Ig-like domains. Homology modeling was used to model human filamin using Modeller 9v5. The resulting model assessed by Verify 3D and PROCHECK showed that the final model is reliable. The conformational disorder prediction of hu ...[more]
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