Ontology highlight
ABSTRACT:
SUBMITTER: Kumar S
PROVIDER: S-EPMC3163929 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Bioinformation 20110820 1
GAGA factor (GAF) is involved in both gene activation and gene repression and plays a role in the modulation of chromatin structure. In Drosophila, Trithroax like (Trl) gene encodes the DNA binding protein called GAGA factor (GAF). Trl-GAF binds to GAGA sites through its C2H2 zinc finger domain and has an N-terminal BTB/POZ domain. Identification of Trl-GAF homologue in mouse helps in deeper understanding of the mechanism and function. Conventional alignment tools such as BLAST and FASTA cannot ...[more]