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Efficient Pd-catalyzed amination reactions for heterocycle functionalization.

ABSTRACT: The Pd-catalyzed amination of unprotected benzo-fused heterocycles is reported, which allows for greater flexibility and efficiency in the modification of this important class of molecules. The generality of these simple and efficient procedures is demonstrated through the synthesis of a wide variety of structural types.

SUBMITTER: Henderson JL

PROVIDER: S-EPMC3164313 | biostudies-literature | 2010 Oct

REPOSITORIES: biostudies-literature

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Efficient Pd-catalyzed amination reactions for heterocycle functionalization.

Henderson Jaclyn L JL Buchwald Stephen L SL

Organic letters 20101001 20

The Pd-catalyzed amination of unprotected benzo-fused heterocycles is reported, which allows for greater flexibility and efficiency in the modification of this important class of molecules. The generality of these simple and efficient procedures is demonstrated through the synthesis of a wide variety of structural types. ...[more]

PMID: 20860403

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