Determination of pentapeptide repeat units in Qnr proteins by the structure-based alignment approach.
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ABSTRACT:
SUBMITTER: Park KS
PROVIDER: S-EPMC3165317 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Publications
Determination of pentapeptide repeat units in Qnr proteins by the structure-based alignment approach.
Park Kwang Seung KS Lee Jung Hun JH Jeong Da Un DU Lee Jae Jin JJ Wu Xing X Jeong Byeong Chul BC Kang Choong-Min CM Lee Sang Hee SH
Antimicrobial agents and chemotherapy 20110627 9
The Qnr proteins belong to the pentapeptide repeat protein family. Despite each pentapeptide repeat unit being an important structural determinant, accurately determining pentapeptide repeat units in the Qnr proteins through sequence-based alignments has been challenging. In the present study, the pentapeptide repeat units of the nine representative Qnr proteins have been precisely determined via the structure-based alignment approach using homology modeling and superposition of their best model ...[more]
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