Ontology highlight
ABSTRACT:
SUBMITTER: Lind GE
PROVIDER: S-EPMC3166273 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Lind Guro E GE Danielsen Stine A SA Ahlquist Terje T Merok Marianne A MA Andresen Kim K Skotheim Rolf I RI Hektoen Merete M Rognum Torleiv O TO Meling Gunn I GI Hoff Geir G Bretthauer Michael M Thiis-Evensen Espen E Nesbakken Arild A Lothe Ragnhild A RA
Molecular cancer 20110721
<h4>Background</h4>The presence of cancer-specific DNA methylation patterns in epithelial colorectal cells in human feces provides the prospect of a simple, non-invasive screening test for colorectal cancer and its precursor, the adenoma. This study investigates a panel of epigenetic markers for the detection of colorectal cancer and adenomas.<h4>Methods</h4>Candidate biomarkers were subjected to quantitative methylation analysis in test sets of tissue samples from colorectal cancers, adenomas, ...[more]