Ontology highlight
ABSTRACT:
SUBMITTER: Blencowe BJ
PROVIDER: S-EPMC316672 | biostudies-literature | 1998 Apr
REPOSITORIES: biostudies-literature
Blencowe B J BJ Issner R R Nickerson J A JA Sharp P A PA
Genes & development 19980401 7
The nuclear matrix antigen recognized by the monoclonal antibody (mAb) B1C8 is a novel serine (S) and arginine (R)-rich protein associated with splicing complexes and is named here SRm160 (SR-related matrix protein of 160 kD). SRm160 contains multiple SR repeats, but unlike proteins of the SR family of splicing factors, lacks an RNA recognition motif. SRm160 and a related protein SRm300 (the 300-kD nuclear matrix antigen recognized by mAb B4A11) form a complex that is required for the splicing o ...[more]