Ontology highlight
ABSTRACT:
SUBMITTER: Muncan V
PROVIDER: S-EPMC3167062 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Muncan Vanesa V Heijmans Jarom J Krasinski Stephen D SD Büller Nikè V NV Wildenberg Manon E ME Meisner Sander S Radonjic Marijana M Stapleton Kelly A KA Lamers Wout H WH Biemond Izak I van den Bergh Weerman Marius A MA O'Carroll Dónal D Hardwick James C JC Hommes Daniel W DW van den Brink Gijs R GR
Nature communications 20110830
In many mammalian species, the intestinal epithelium undergoes major changes that allow a dietary transition from mother's milk to the adult diet at the end of the suckling period. These complex developmental changes are the result of a genetic programme intrinsic to the gut tube, but its regulators have not been identified. Here we show that transcriptional repressor B lymphocyte-induced maturation protein 1 (Blimp1) is highly expressed in the developing and postnatal intestinal epithelium unti ...[more]