Ontology highlight
ABSTRACT:
SUBMITTER: Eapen M
PROVIDER: S-EPMC3167362 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Eapen Mary M Le Rademacher Jennifer J Antin Joseph H JH Champlin Richard E RE Carreras Jeanette J Fay Joseph J Passweg Jakob R JR Tolar Jakub J Horowitz Mary M MM Marsh Judith C W JC Deeg H Joachim HJ
Blood 20110615 9
Outcome after unrelated donor bone marrow (BM) transplantation for severe aplastic anemia (SAA) has improved, with survival rates now approximately 75%. Increasing use of peripheral blood stem and progenitor cells (PBPCs) instead of BM as a graft source prompted us to compare outcomes of PBPC and BM transplantation for SAA. We studied 296 patients receiving either BM (n = 225) or PBPC (n = 71) from unrelated donors matched at human leukocyte antigen-A, -B, -C, -DRB1. Hematopoietic recovery was s ...[more]