Genetic analysis of a novel human adenovirus with a serologically unique hexon and a recombinant fiber gene.
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ABSTRACT:
SUBMITTER: Liu EB
PROVIDER: S-EPMC3168504 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
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Genetic analysis of a novel human adenovirus with a serologically unique hexon and a recombinant fiber gene.
Liu Elizabeth B EB Ferreyra Leonardo L Ferreyra Leonardo L Fischer Stephen L SL Pavan Jorge V JV Nates Silvia V SV Hudson Nolan Ryan NR Tirado Damaris D Dyer David W DW Chodosh James J Seto Donald D Jones Morris S MS
PloS one 20110907 9
In February of 1996 a human adenovirus (formerly known as Ad-Cor-96-487) was isolated from the stool of an AIDS patient who presented with severe chronic diarrhea. To characterize this apparently novel pathogen of potential public health significance, the complete genome of this adenovirus was sequenced to elucidate its origin. Bioinformatic and phylogenetic analyses of this genome demonstrate that this virus, heretofore referred to as HAdV-D58, contains a novel hexon gene as well as a recombina ...[more]
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