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Cationic gold(I) axially chiral biaryl bisphosphine complex-catalyzed atropselective synthesis of heterobiaryls.

ABSTRACT: It has been established that a cationic gold(I)/(R)-DTBM-Segphos or (R)-BINAP complex catalyzes the atropselective intramolecular hydroarylation of alkynes leading to enantioenriched axially chiral 4-aryl-2-quinolinones and 4-arylcoumarins with up to 61% ee.

SUBMITTER: Shibuya T

PROVIDER: S-EPMC3170204 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature

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Cationic gold(I) axially chiral biaryl bisphosphine complex-catalyzed atropselective synthesis of heterobiaryls.

Shibuya Tetsuro T Nakamura Kyosuke K Tanaka Ken K

Beilstein journal of organic chemistry 20110706

It has been established that a cationic gold(I)/(R)-DTBM-Segphos or (R)-BINAP complex catalyzes the atropselective intramolecular hydroarylation of alkynes leading to enantioenriched axially chiral 4-aryl-2-quinolinones and 4-arylcoumarins with up to 61% ee. ...[more]

PMID: 21915192

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