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Enantioselective hydroformylation of aniline derivatives.


ABSTRACT: We have developed a ligand that reversibly binds to aniline substrates, allowing for the control of regioselectivity and enantioselectivity in hydroformylation. In this paper we address how the electronics of the aniline ring affect both the binding of the substrate to the ligand and the enantioselectivity in this reaction.

SUBMITTER: Joe CL 

PROVIDER: S-EPMC3170429 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature

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Enantioselective hydroformylation of aniline derivatives.

Joe Candice L CL   Tan Kian L KL  

The Journal of organic chemistry 20110815 18


We have developed a ligand that reversibly binds to aniline substrates, allowing for the control of regioselectivity and enantioselectivity in hydroformylation. In this paper we address how the electronics of the aniline ring affect both the binding of the substrate to the ligand and the enantioselectivity in this reaction. ...[more]

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