Ontology highlight
ABSTRACT:
SUBMITTER: Okamoto H
PROVIDER: S-EPMC3170568 | biostudies-literature | 2011 Aug
REPOSITORIES: biostudies-literature
Okamoto Hiroshi H Kobayashi Akiko A
Journal of inflammation (London, England) 20110824
Rheumatoid arthritis (RA) is an inflammatory, polyarticular joint disease. A number of cellular responses are involved in the pathogenesis of rheumatoid arthritis, including activation of inflammatory cells and cytokine expression. The cellular responses involved in each of these processes depends on the specific signaling pathways that are activated; many of which include protein tyrosine kinases. These pathways include the mitogen-activated protein kinase pathway, Janus kinases/signal transduc ...[more]