Ontology highlight
ABSTRACT:
SUBMITTER: Suhane S
PROVIDER: S-EPMC3171595 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Biochemical and biophysical research communications 20110816 4
We present evidence for potential biomarker utility of a mitochondrial complex I subunit, (NDUFS3) in discriminating normal and highly invasive breast carcinoma specimens obtained from clinical patients. Besides being a robust indicator of breast cancer aggressiveness, NDUFS3 also shows clear signatures of a hypoxia/necrosis marker in invasive ductal carcinoma specimens. Statistically significant positive correlation was observed between nuclear grade and NDUFS3 expression level in the tumor spe ...[more]