Ontology highlight
ABSTRACT:
SUBMITTER: Ouillette P
PROVIDER: S-EPMC3175782 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Ouillette Peter P Collins Roxane R Shakhan Sajid S Li Jinghui J Peres Edward E Kujawski Lisa L Talpaz Moshe M Kaminski Mark M Li Cheng C Shedden Kerby K Malek Sami N SN
Blood 20110727 11
Genomic aberrations are of predominant importance to the biology and clinical outcome of patients with chronic lymphocytic leukemia (CLL), and FISH-based genomic risk classifications are routinely used in clinical decision making in CLL. One of the known limitations of CLL FISH is the inability to comprehensively interrogate the CLL genome for genomic changes. In an effort at overcoming the existing limitations in CLL genome analysis, we have analyzed high-purity DNA isolated from FACS-sorted CD ...[more]