Protein signatures for survival and recurrence in metastatic melanoma.
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ABSTRACT:
SUBMITTER: Hardesty WM
PROVIDER: S-EPMC3178099 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Publications
Protein signatures for survival and recurrence in metastatic melanoma.
Hardesty William M WM Kelley Mark C MC Mi Deming D Low Robert L RL Caprioli Richard M RM
Journal of proteomics 20110423 7
Patients with melanoma metastatic to regional lymph nodes exhibit a range in tumor progression, survival, and treatment. Current approaches to stratify patients with this stage of disease predominantly involve clinical and histological methods. Molecular classification thus far has focused almost exclusively on genetic mutations. In this study, proteomic data from 69 melanoma lymph node metastases and 17 disease free lymph nodes acquired by histology-directed MALDI imaging mass spectrometry were ...[more]
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