Ontology highlight
ABSTRACT:
SUBMITTER: Wu C
PROVIDER: S-EPMC3178556 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Wu Cen C Li Gengxin G Zhu Jun J Cui Yuehua Y
PloS one 20110922 9
Functional mapping has been a powerful tool in mapping quantitative trait loci (QTL) underlying dynamic traits of agricultural or biomedical interest. In functional mapping, multivariate normality is often assumed for the underlying data distribution, partially due to the ease of parameter estimation. The normality assumption however could be easily violated in real applications due to various reasons such as heavy tails or extreme observations. Departure from normality has negative effect on te ...[more]