Ontology highlight
ABSTRACT:
SUBMITTER: Bondy B
PROVIDER: S-EPMC3181738 | biostudies-literature | 2005
REPOSITORIES: biostudies-literature
Dialogues in clinical neuroscience 20050101 3
Genetic factors are believed to play a major role in the variation of treatment response and the incidence of adverse effects to medication. The aim of pharmacogenetics is to elucidate this variability according to hereditary differences. Considering current hypotheses for the mechanisms of action of antidepressants, most investigations to date have concentrated on mutations in genes coding either for the pathways in the serotonergic and noradrenergic systems or for drug-metabolizing enzymes. Re ...[more]