Ontology highlight
ABSTRACT:
SUBMITTER: Hsu HF
PROVIDER: S-EPMC3183162 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Hsu Hsin-Fang HF Ngo Khanh V KV Chitteni-Pattu Sindhu S Cox Michael M MM Li Hung-Wen HW
Biochemistry 20110906 39
With the aid of an efficient, precise, and almost error-free DNA repair system, Deinococcus radiodurans can survive hundreds of double-strand breaks inflicted by high doses of irradiation or desiccation. RecA of D. radiodurans (DrRecA) plays a central role both in the early phase of repair by an extended synthesis-dependent strand annealing process and in the later more general homologous recombination phase. Both roles likely require DrRecA filament formation on duplex DNA. We have developed si ...[more]