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Identification and phylogenetic analysis of Japanese Macaque Babesia-1 (JM-1) detected from a Japanese Macaque (Macaca fuscata fuscata).

ABSTRACT: We demonstrate here the identification and phylogenetic characterization of Babesia microti (B. microti)-like parasite detected from a splenectomized Japanese macaque (Macaca fuscata fuscata) at a facility for laboratory animal science. On Day 133 after splenectomy, intra-erythrocytic parasites were found on light microscopic examination, and the level of parasitemia reached 0.3% on blood smear. Molecular characterization of the parasite using nested-polymerization chain reactions targeting the 18S rRNA, ?-tubulin, and subunit 7 (eta) of the chaperonin-containing t-complex polypeptide 1 (CCT7) genes were identified as a B. microti-like parasite, designated the Japanese Macaque Babesia-1 (JM-1).

SUBMITTER: Hirata H

PROVIDER: S-EPMC3183768 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature

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Identification and phylogenetic analysis of Japanese Macaque Babesia-1 (JM-1) detected from a Japanese Macaque (Macaca fuscata fuscata).

Hirata Haruyuki H Kawai Satoru S Maeda Mari M Jinnai Michio M Fujisawa Kohei K Katakai Yuko Y Hikosaka Kenji K Tanabe Kazuyuki K Yasutomi Yasuhiro Y Ishihara Chiaki C

The American journal of tropical medicine and hygiene 20111001 4

We demonstrate here the identification and phylogenetic characterization of Babesia microti (B. microti)-like parasite detected from a splenectomized Japanese macaque (Macaca fuscata fuscata) at a facility for laboratory animal science. On Day 133 after splenectomy, intra-erythrocytic parasites were found on light microscopic examination, and the level of parasitemia reached 0.3% on blood smear. Molecular characterization of the parasite using nested-polymerization chain reactions targeting the ...[more]

PMID: 21976563

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| S-EPMC6233195 | biostudies-literature

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