Ontology highlight
ABSTRACT:
SUBMITTER: Berardo A
PROVIDER: S-EPMC3185833 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Berardo A A Musumeci O O Toscano A A
Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology 20110601 1
Mitochondrial Respiratory Chain Disorders (MRCD) are a heterogeneous group of disorders that share the involvement of the cellular bioenergetic machinery due to molecular defects affecting the mitochondrial oxidative phosphorylation system (OXPHOS). Clinically, they usually involve multiple tissues although they tend to mainly affect nervous system and skeletal muscle. Cardiological manifestations are frequent and include hypertrophic or dilated cardiomyopathies and heart conduction defects, bei ...[more]