Ontology highlight
ABSTRACT:
SUBMITTER: Muller BU
PROVIDER: S-EPMC3186238 | biostudies-literature | 2011 May
REPOSITORIES: biostudies-literature
Müller B U BU Stich B B Piepho H-P HP
Heredity 20101020 5
Control of the genome-wide type I error rate (GWER) is an important issue in association mapping and linkage mapping experiments. For the latter, different approaches, such as permutation procedures or Bonferroni correction, were proposed. The permutation test, however, cannot account for population structure present in most association mapping populations. This can lead to false positive associations. The Bonferroni correction is applicable, but usually on the conservative side, because correla ...[more]