Ontology highlight
ABSTRACT:
SUBMITTER: Schwendener S
PROVIDER: S-EPMC3187003 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Schwendener Sybille S Perreten Vincent V
Antimicrobial agents and chemotherapy 20110718 10
A novel streptogramin A, pleuromutilin, and lincosamide resistance determinant, Vga(E), was identified in porcine methicillin-resistant Staphylococcus aureus (MRSA) ST398. The vga(E) gene encoded a 524-amino-acid protein belonging to the ABC transporter family. It was found on a multidrug resistance-conferring transposon, Tn6133, which was comprised of Tn554 with a stably integrated 4,787-bp DNA sequence harboring vga(E). Detection of Tn6133 in several porcine MRSA ST398 isolates and its ability ...[more]