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Detection of Mycoplasma genitalium-reactive cervicovaginal antibodies among infected women.

ABSTRACT: Mycoplasma genitalium-reactive cervicovaginal IgA and IgG antibodies were detected in 51.9% and 70.4% of 27 infected women and 22.2% and 18.5% of 27 uninfected controls, respectively. The predominance of MgpB- and MgpC-reactive antibodies at the site of infection is consistent with their hypothesized role in selecting antigenic variants during persistent infection.

SUBMITTER: Iverson-Cabral SL 

PROVIDER: S-EPMC3187045 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature

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Detection of Mycoplasma genitalium-reactive cervicovaginal antibodies among infected women.

Iverson-Cabral Stefanie L SL   Manhart Lisa E LE   Totten Patricia A PA  

Clinical and vaccine immunology : CVI 20110803 10

Mycoplasma genitalium-reactive cervicovaginal IgA and IgG antibodies were detected in 51.9% and 70.4% of 27 infected women and 22.2% and 18.5% of 27 uninfected controls, respectively. The predominance of MgpB- and MgpC-reactive antibodies at the site of infection is consistent with their hypothesized role in selecting antigenic variants during persistent infection. ...[more]

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