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Genome sequence of Mycobacterium bovis BCG Moreau, the Brazilian vaccine strain against tuberculosis.

ABSTRACT: Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the only vaccine available against tuberculosis, and the strains used worldwide represent a family of daughter strains with distinct genotypic characteristics. Here we report the complete genome sequence of M. bovis BCG Moreau, the strain in continuous use in Brazil for vaccine production since the 1920s.

SUBMITTER: Gomes LH 

PROVIDER: S-EPMC3187452 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature

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Genome sequence of Mycobacterium bovis BCG Moreau, the Brazilian vaccine strain against tuberculosis.

Gomes Leonardo H F LH   Otto Thomas D TD   Vasconcellos Erico A EA   Ferrão Patrícia M PM   Maia Renata M RM   Moreira Aline S AS   Ferreira Marcelo A MA   Castello-Branco Luiz R R LR   Degrave Wim M WM   Mendonça-Lima Leila L  

Journal of bacteriology 20111001 19

Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the only vaccine available against tuberculosis, and the strains used worldwide represent a family of daughter strains with distinct genotypic characteristics. Here we report the complete genome sequence of M. bovis BCG Moreau, the strain in continuous use in Brazil for vaccine production since the 1920s. ...[more]

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