Ontology highlight
ABSTRACT:
SUBMITTER: Mujugira A
PROVIDER: S-EPMC3187805 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Mujugira Andrew A Baeten Jared M JM Donnell Deborah D Ndase Patrick P Mugo Nelly R NR Barnes Linda L Campbell James D JD Wangisi Jonathan J Tappero Jordan W JW Bukusi Elizabeth E Cohen Craig R CR Katabira Elly E Ronald Allan A Tumwesigye Elioda E Were Edwin E Fife Kenneth H KH Kiarie James J Farquhar Carey C John-Stewart Grace G Kidoguchi Lara L Panteleeff Dana D Krows Meighan M Shah Heena H Revall Jennifer J Morrison Susan S Ondrejcek Lisa L Ingram Charlotte C Coombs Robert W RW Lingappa Jairam R JR Celum Connie C
PloS one 20111005 10
<h4>Introduction</h4>Stable heterosexual HIV-1 serodiscordant couples in Africa have high HIV-1 transmission rates and are a critical population for evaluation of new HIV-1 prevention strategies. The Partners PrEP Study is a randomized, double-blind, placebo-controlled trial of tenofovir and emtricitabine-tenofovir pre-exposure prophylaxis to decrease HIV-1 acquisition within heterosexual HIV-1 serodiscordant couples. We describe the trial design and characteristics of the study cohort.<h4>Metho ...[more]