Dynamic clamp with StdpC software.
Ontology highlight
ABSTRACT:
SUBMITTER: Kemenes I
PROVIDER: S-EPMC3188375 | biostudies-literature | 2011 Mar
REPOSITORIES: biostudies-literature
Publications
Dynamic clamp with StdpC software.
Kemenes Ildikó I Marra Vincenzo V Crossley Michael M Samu Dávid D Staras Kevin K Kemenes György G Nowotny Thomas T
Nature protocols 20110303 3
Dynamic clamp is a powerful method that allows the introduction of artificial electrical components into target cells to simulate ionic conductances and synaptic inputs. This method is based on a fast cycle of measuring the membrane potential of a cell, calculating the current of a desired simulated component using an appropriate model and injecting this current into the cell. Here we present a dynamic clamp protocol using free, fully integrated, open-source software (StdpC, for spike timing-dep ...[more]
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