Ontology highlight
ABSTRACT:
SUBMITTER: Rivera-Amill V
PROVIDER: S-EPMC3188391 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
Rivera-Amill Vanessa V Noel Richard J RJ Orsini Suheydi S Tirado Griselle G García José M JM Buch Shilpa S Kumar Anil A
Virology 20060928 2
We analyzed the association between the evolution of the V3-V5 regions of env and disease progression in our SIV/SHIV macaque model of morphine dependence and AIDS. Previous studies revealed two distinct disease patterns--fast progression and normal progression. To determine the effect of the two distinct patterns of disease in the evolution of SIV/17E-Fr envelope, we analyzed env sequences from three morphine-dependent macaques that developed accelerated AIDS and three morphine-dependent macaqu ...[more]