Ontology highlight
ABSTRACT:
SUBMITTER: Villegas R
PROVIDER: S-EPMC3189704 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Villegas Raquel R Williams Scott S Gao Yutang Y Cai Qiuyin Q Li Honglan H Elasy Tom T Cai Hui H Edwards Todd T Xiang Yong-Bing YB Zheng Wei W Long Jirong J Ou Shu Xiao X
Annals of human genetics 20110901 5
Animal studies have shown that the peroxime proliferator-activated receptor delta (PPARD) gene regulates glucose metabolism and insulin sensitivity. Genetic variation in the PPARD gene might affect physical endurance and has been associated with obesity. We investigated the independent and modifying effect of variants in the PPARD gene with exercise participation and body mass index (BMI) on type 2 diabetes (T2D), using data from a genome-wide association study (GWAS) of middle-aged women living ...[more]