Ontology highlight
ABSTRACT:
SUBMITTER: Maffre P
PROVIDER: S-EPMC3190609 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Maffre Pauline P Nienhaus Karin K Amin Faheem F Parak Wolfgang J WJ Nienhaus G Ulrich GU
Beilstein journal of nanotechnology 20110712
Using dual-focus fluorescence correlation spectroscopy, we have analyzed the adsorption of three human blood serum proteins, namely serum albumin, apolipoprotein A-I and apolipoprotein E4, onto polymer-coated, fluorescently labeled FePt nanoparticles (~12 nm diameter) carrying negatively charged carboxyl groups on their surface. For all three proteins, a step-wise increase in hydrodynamic radius with protein concentration was observed, strongly suggesting the formation of protein monolayers that ...[more]