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Dendron-mediated self-assembly of highly PEGylated block copolymers: a modular nanocarrier platform.

ABSTRACT: PEGylated dendron coils (PDCs) were investigated as a novel potential nanocarrier platform. PDCs self-assembled into micelles at lower CMCs than linear copolymer counterparts by 1-2 orders of magnitude, due to the unique architecture of dendrons. MD simulations also supported thermodynamically favourable self-assembly mediated by dendrons.

SUBMITTER: Bae JW

PROVIDER: S-EPMC3190671 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature

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Dendron-mediated self-assembly of highly PEGylated block copolymers: a modular nanocarrier platform.

Bae Jin Woo JW Pearson Ryan M RM Patra Niladri N Sunoqrot Suhair S Vuković Lela L Král Petr P Hong Seungpyo S

Chemical communications (Cambridge, England) 20110822 37

PEGylated dendron coils (PDCs) were investigated as a novel potential nanocarrier platform. PDCs self-assembled into micelles at lower CMCs than linear copolymer counterparts by 1-2 orders of magnitude, due to the unique architecture of dendrons. MD simulations also supported thermodynamically favourable self-assembly mediated by dendrons. ...[more]

PMID: 21858356

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