Ontology highlight
ABSTRACT:
SUBMITTER: Tseng YF
PROVIDER: S-EPMC3192705 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
PloS one 20111013 10
Current egg-based influenza vaccine production technology can't promptly meet the global demand during an influenza pandemic as shown in the 2009 H1N1 pandemic. Moreover, its manufacturing capacity would be vulnerable during pandemics caused by highly pathogenic avian influenza viruses. Therefore, vaccine production using mammalian cell technology is becoming attractive. Current influenza H5N1 vaccine strain (NIBRG-14), a reassortant virus between A/Vietnam/1194/2004 (H5N1) virus and egg-adapted ...[more]