Attract: A method for identifying core pathways that define cellular phenotypes.
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ABSTRACT:
SUBMITTER: Mar JC
PROVIDER: S-EPMC3194807 | biostudies-literature | 2011
REPOSITORIES: biostudies-literature
Publications
attract: A method for identifying core pathways that define cellular phenotypes.
Mar Jessica C JC Matigian Nicholas A NA Quackenbush John J Wells Christine A CA
PloS one 20111014 10
attract is a knowledge-driven analytical approach for identifying and annotating the gene-sets that best discriminate between cell phenotypes. attract finds distinguishing patterns within pathways, decomposes pathways into meta-genes representative of these patterns, and then generates synexpression groups of highly correlated genes from the entire transcriptome dataset. attract can be applied to a wide range of biological systems and is freely available as a Bioconductor package and has been in ...[more]
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