Structural basis for cytokinin recognition by Arabidopsis thaliana histidine kinase 4.
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ABSTRACT:
SUBMITTER: Hothorn M
PROVIDER: S-EPMC3197759 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Publications
Structural basis for cytokinin recognition by Arabidopsis thaliana histidine kinase 4.
Hothorn Michael M Dabi Tsegaye T Chory Joanne J
Nature chemical biology 20111002 11
Cytokinins are classic hormones that orchestrate plant growth and development and the integrity of stem cell populations. Cytokinin receptors are eukaryotic sensor histidine kinases that are activated by both naturally occurring adenine-type cytokinins and urea-based synthetic compounds. Crystal structures of the Arabidopsis thaliana histidine kinase 4 sensor domain in complex with different cytokinin ligands now rationalize the hormone-binding specificity of the receptor and may spur the design ...[more]
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