Hippocampal volume is related to body mass index in Alzheimer's disease.
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ABSTRACT:
SUBMITTER: Ho AJ
PROVIDER: S-EPMC3197837 | biostudies-literature | 2011 Jan
REPOSITORIES: biostudies-literature
Publications
Hippocampal volume is related to body mass index in Alzheimer's disease.
Ho April J AJ Raji Cyrus A CA Saharan Priya P DeGiorgio Andrew A Madsen Sarah K SK Hibar Derrek P DP Stein Jason L JL Becker James T JT Lopez Oscar L OL Toga Arthur W AW Thompson Paul M PM
Neuroreport 20110101 1
Obesity is associated with lower brain volumes in early Alzheimer's disease, but its effects on hippocampal volumes are unclear, as weight loss is also associated with Alzheimer's disease. To address this question, we applied an automated hippocampal mapping method to brain MRI scans for 162 patients with Alzheimer's disease. We hypothesized that obesity, measured by body mass index, would be associated with lower hippocampal volumes in mildly affected patients. Statistical maps showed a selecti ...[more]
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