Ontology highlight
ABSTRACT:
SUBMITTER: Singh SP
PROVIDER: S-EPMC3197944 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Singh Shashi P SP Gundavarapu Sravanthi S Peña-Philippides Juan C JC Rir-Sima-ah Jules J Mishra Neerad C NC Wilder Julie A JA Langley Raymond J RJ Smith Kevin R KR Sopori Mohan L ML
Journal of immunology (Baltimore, Md. : 1950) 20110919 9
Parental, particularly maternal, smoking increases the risk for childhood allergic asthma and infection. Similarly, in a murine allergic asthma model, prenatal plus early postnatal exposure to secondhand cigarette smoke (SS) exacerbates airways hyperreactivity and Th2 responses in the lung. However, the mechanism and contribution of prenatal versus early postnatal SS exposure on allergic asthma remain unresolved. To identify the effects of prenatal and/or early postnatal SS on allergic asthma, B ...[more]