Ontology highlight
ABSTRACT:
SUBMITTER: Feenstra I
PROVIDER: S-EPMC3198145 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Feenstra Ilse I Hanemaaijer Nicolien N Sikkema-Raddatz Birgit B Yntema Helger H Dijkhuizen Trijnie T Lugtenberg Dorien D Verheij Joke J Green Andrew A Hordijk Roel R Reardon William W Vries Bert de Bd Brunner Han H Bongers Ernie E Leeuw Nicole de Nd van Ravenswaaij-Arts Conny C
European journal of human genetics : EJHG 20110629 11
High-resolution genome-wide array analysis enables detailed screening for cryptic and submicroscopic imbalances of microscopically balanced de novo rearrangements in patients with developmental delay and/or congenital abnormalities. In this report, we added the results of genome-wide array analysis in 54 patients to data on 117 patients from seven other studies. A chromosome imbalance was detected in 37% of all patients with two-breakpoint rearrangements. In 49% of these patients, the imbalances ...[more]