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Therapeutic advances in women's cancers.

ABSTRACT: Cytotoxic therapy and surgery have improved outcomes for patients with gynecologic malignancies over the last twenty years, but women's cancers still account for over ten percent of cancer related deaths annually. Insights into the pathogenesis of cancer have led to the development of drugs that target molecular pathways essential to tumor survival including angiogenesis, DNA repair, and apoptosis. This review outlines several of the promising new biologically targeted drugs currently being tested to treat gynecologic malignancies.

SUBMITTER: Carroll AR

PROVIDER: S-EPMC3199127 | biostudies-literature | 2011 Jan

REPOSITORIES: biostudies-literature

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Therapeutic advances in women's cancers.

Carroll Amy R AR Coleman Robert L RL Sood Anil K AK

Frontiers in bioscience (Scholar edition) 20110101 1

Cytotoxic therapy and surgery have improved outcomes for patients with gynecologic malignancies over the last twenty years, but women's cancers still account for over ten percent of cancer related deaths annually. Insights into the pathogenesis of cancer have led to the development of drugs that target molecular pathways essential to tumor survival including angiogenesis, DNA repair, and apoptosis. This review outlines several of the promising new biologically targeted drugs currently being test ...[more]

PMID: 21196359

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