Ontology highlight
ABSTRACT:
SUBMITTER: Nagy KJ
PROVIDER: S-EPMC3202337 | biostudies-literature | 2011 Sep
REPOSITORIES: biostudies-literature
Nagy Katelyn J KJ Giano Michael C MC Jin Albert A Pochan Darrin J DJ Schneider Joel P JP
Journal of the American Chemical Society 20110907 38
Chirality can be used as a design tool to control the mechanical rigidity of hydrogels formed from self-assembling peptides. Hydrogels prepared from enantiomeric mixtures of self-assembling β-hairpins show nonadditive, synergistic, enhancement in material rigidity compared to gels prepared from either pure enantiomer, with the racemic hydrogel showing the greatest effect. CD spectroscopy, TEM, and AFM indicate that this enhancement is defined by nanoscale interactions between enantiomers in the ...[more]