Ontology highlight
ABSTRACT:
SUBMITTER: Banitt I
PROVIDER: S-EPMC3203577 | biostudies-literature | 2011 Nov
REPOSITORIES: biostudies-literature
Nucleic acids research 20110810 20
Accurate prediction of protein-DNA complexes could provide an important stepping stone towards a thorough comprehension of vital intracellular processes. Few attempts were made to tackle this issue, focusing on binding patch prediction, protein function classification and distance constraints-based docking. We introduce ParaDock: a novel ab initio protein-DNA docking algorithm. ParaDock combines short DNA fragments, which have been rigidly docked to the protein based on geometric complementarity ...[more]